Before entering the Krebs cycle, pyruvate is converted to which molecule?

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Prepare for the AQA A-Level PE Energy Systems Exam. Study with comprehensive flashcards and multiple-choice questions, featuring hints and explanations. Ace your exam with confidence!

Multiple Choice

Before entering the Krebs cycle, pyruvate is converted to which molecule?

Explanation:
Conversion of pyruvate to acetyl-CoA links glycolysis to the Krebs cycle. The pyruvate dehydrogenase complex removes a carbon as CO2, generates NADH, and attaches the remaining two-carbon acetyl group to CoA. This acetyl-CoA then enters the Krebs cycle by combining with oxaloacetate to form citrate. Lactate is produced from pyruvate under anaerobic conditions, while oxaloacetate and malate are intermediates within the cycle itself, not the direct product from pyruvate before entry.

Conversion of pyruvate to acetyl-CoA links glycolysis to the Krebs cycle. The pyruvate dehydrogenase complex removes a carbon as CO2, generates NADH, and attaches the remaining two-carbon acetyl group to CoA. This acetyl-CoA then enters the Krebs cycle by combining with oxaloacetate to form citrate. Lactate is produced from pyruvate under anaerobic conditions, while oxaloacetate and malate are intermediates within the cycle itself, not the direct product from pyruvate before entry.

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