Where does the Krebs cycle occur?

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Prepare for the AQA A-Level PE Energy Systems Exam. Study with comprehensive flashcards and multiple-choice questions, featuring hints and explanations. Ace your exam with confidence!

Multiple Choice

Where does the Krebs cycle occur?

Explanation:
The Krebs cycle takes place in the mitochondrial matrix. In eukaryotic cells, glycolysis happens in the cytoplasm, then pyruvate enters the mitochondrion and is converted to acetyl-CoA in the matrix. The cycle’s enzymes reside in the matrix, driving the oxidation of acetyl-CoA to CO2 and producing NADH and FADH2 to feed the electron transport chain on the inner mitochondrial membrane. The other locations don’t fit because glycolysis occurs in the cytoplasm, the nucleus contains DNA and transcription machinery, and ribosomes are the sites of protein synthesis, not the Krebs cycle.

The Krebs cycle takes place in the mitochondrial matrix. In eukaryotic cells, glycolysis happens in the cytoplasm, then pyruvate enters the mitochondrion and is converted to acetyl-CoA in the matrix. The cycle’s enzymes reside in the matrix, driving the oxidation of acetyl-CoA to CO2 and producing NADH and FADH2 to feed the electron transport chain on the inner mitochondrial membrane. The other locations don’t fit because glycolysis occurs in the cytoplasm, the nucleus contains DNA and transcription machinery, and ribosomes are the sites of protein synthesis, not the Krebs cycle.

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